In this talk, I will present some recent and old results on measurements of round-trip time of TCP connections over a large scale sampleof the Internet. In particular I will address two questions: 1) "Is the Round-trip Time Correlated with the Number of Packets in Flight?" (a paper by Saad Biaz, and Nitin H. Vaidya) and 2) What is the "Variability in TCP Round-trip Times"? (a paper by Jay Aikat, Jasleen Kaur, F. Donelson Smith, and Kevin Jeffay). Both papers appeared in IMC'03. Then I will discuss the consequences of these answers to the problem of distiguishing congestion losses from wireless transmission losses in wire/wireless hybrid networks. Finally, I'm going to present a related problem that I'm working on in collaboration with Mark to use extra RTT information to detect packet losses for the cases when TCP has to rely on timeouts.